Integrin CD11c/CD18 α-Chain Phosphorylation Is Functionally Important
نویسندگان
چکیده
منابع مشابه
Integrin CD11c/CD18 -Chain Phosphorylation Is Functionally
Background: Leukocyte integrins are involved in cell adhesion, cell migration, and phagocytosis. Results: CD11c/CD18, a leukocyte integrin expressed on monocytes, macrophages, and dendritic cells, is phosphorylated on Ser-1158 of the -chain. Abrogation of phosphorylation results in impaired adhesion and phagocytosis. Conclusion: Integrin inside-out activated adhesion is regulated by a single ph...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.c113.497446